.Can PHL handle a A380? Terminal wise?
Nope. However, if they extend A-West South - which was a plan awhile back, a potential 380 gate could be designed. I think the major problem would be a double decker loading bridge and enough gate separation to accommodate the wing span. In the past both BA and LH have used 747s into PHL, but the 380s wingspan is about 50 Feet Wider. Not certain if the runway would need reinforcement. 9R/27L is already 200 Feet wide, so width is no problem and it's being extended to 12,000 feet - even though that's not really a 380 requirement - even at MTOW.
On topic - one fairly certain route starting next year will be PHL-DOH on QR. Otherwise, we'll just have to wait and see how Parker establishes the JFK-PHL relationship to really determine where international traffic flows. PDEW may be secondary in guessing PHL route potential, since historically it has increased dramatically once non-stop service is established and it's even more likely to do so within the NYC-PHL megalopolis. Bet we'll see subtle signs of the futures for PHL, CLT and PHX fairly soon.
PIT-CDG service is no longer subsidized.