No more than it mattered that Southwest doesn't fly to SJU. But you saw fit to comment, so I thought I'd add to it. I mean, I rarely book a flight between two US cities and ask myself "Does this airline or a code share partner serve Shanghai"? Does it matter when I only want to go to Nashville? If Southwest doesn't fly where I'm going, I'll fly an airline that does.
And as a result you lose those "free" trips to your vacation destination. Perhaps it is the small town mentality that has you fixated on not realizing the world is where business works. Not the OH valley.
Did you happen to catch the chart in the USA today business section today? Good graph on the business and leisure traveler seeking services on the non LCC airline.
As for Shanghai I suspect that you are not going to be going there anyway.