Casting my vote for SYR as a new city. Good O/D, best economy in Upstate NY, many colleges and universities in the area, a large Army installation an hour north. Direct access to I-81 (Binghamton area, Watertown/Ft. Drum, and Kingston/Ottawa area) and close to I-90 as well. While not the size of CLT, MSP, or CVG, SYR would be very successful from the get-go.